MOTS-c

What is MOTS-c and how does it work?

MOTS-c is a 16-amino acid mitochondrial peptide produced mainly in muscles. It’s also detectable in other tissues and in the blood

Exercise generally boosts MOTS-c levels, so MOTS-c administration replicates many of the benefits of exercise

Starting at $200

MITOCHONDRIA HEALTH

METABOLISM

ANTI-AGING

HORMONE BALANCE

BRAIN HEALTH

ANTI-INFLAMMATORY

Protects the cells
Maintains mitochondrial function and cellular viability under stressful conditions
Regulates metabolic homeostasis
May mitigate diet-induced insulin resistance and obesity
Inhibits purine biosynthesis
Activates 5’adenosine monophosphate-activated protein kinase (AMPK), increasing fat oxidation
Increases transport of fatty acids into the mitochondria to burn for energy
Increases fat burning and reduces production of new fat molecules
Improves glucose uptake by bringing glucose transporter 4 (Glut4) in muscles
Activates peroxisome proliferator-activated receptor-gamma coactivator (PGC-1alpha), which increases the generation of new and healthy mitochondria.
PGC-1alpha then activates nuclear respiratory factors (Nrf1 and Nrf2), which turns on many antioxidant genes.
Increases calorie burn as heat production by increasing brown fat and mitochondrial uncoupling using uncoupling protein 1 (UCP-1)
Preserves mitochondrial function and bone mass in a mouse menopause model, with biochemical effects similar to exercise
Improves athletic performance
Supports weight loss effort in combination with diet and exercise
May improve strength and muscle gain by modulating myostatin
Protects against memory impairment from amyloid beta and lipopolysaccharides (inflammatory bacterial toxins from leaky gut) in a mouse model with intranasal delivery
May boost longevity